Semaglutide: Tiv Thaiv Kab Mob Ntshav Qab Zib

Semaglutide yog glucagon-zoo li peptide-1 (GLP-1) receptor agonist uas txo cov ntshav qab zib los ntawm kev ua raws li kev ua ntawm GLP-1. Nyob rau hauv xyoo tas los no, daim ntawv thov ntawm semaglutide nyob rau hauv daim teb ntawm cov kab mob plawv tau nyiam cov neeg tuaj saib. Raws li kev tshawb fawb tshiab thiab kev sim tshuaj ntsuam xyuas, semaglutide tsis yog tsuas yog ua tau zoo hauv kev txo cov ntshav qab zib, tab sis kuj qhia txog cov txiaj ntsig tseem ceeb hauv kev tiv thaiv kab mob plawv.

Ua ntej, semaglutide muaj cov nyhuv tseem ceeb ntawm cov ntshav qabzib-txo qis. Hauv SUSTAIN series ntawm kev tshawb fawb, semaglutide tuaj yeem txo qis glycated hemoglobin (HbA1c) qib los ntawm 1.8%, uas yog qhov zoo tshaj rau cov ntshav qabzib-txo cov teebmeem ntawm ntau lwm cov tshuaj hypoglycemic. Tsis tas li ntawd, semaglutide kuj tseem tuaj yeem txo qhov hnyav, txo qis systolic ntshav siab, thiab txhim kho lipid spectrum, tag nrho cov no pab txo qis kev pheej hmoo ntawm cov kab mob plawv.

Hais txog kev tiv thaiv kab mob plawv, semaglutide ua haujlwm los ntawm ntau lub tshuab. Nws tuaj yeem txo qhov tsim cov cytokines inflammatory thiab reactive oxygen hom, alleviate zus tau tej cov endothelial adhesion molecules, slows tus tsim ntawm atherosclerotic plaques, thiab inhibit tsim ua npuas ncauj hlwb koom nyob rau hauv tus txheej txheem ntawm atherosclerosis. Tsis tas li ntawd, semaglutide tuaj yeem ncua qhov kev loj hlob ntawm vascular atherosclerosis los ntawm kev ntxhov siab antioxidant, tswj lub cev cov lus teb, thiab txhim kho insulin rhiab heev, txhua yam ua rau kev tiv thaiv kab mob plawv.

Semaglutide kuj tau pom cov txiaj ntsig zoo hauv cov txiaj ntsig ntawm cov hlab plawv. Qhov kev sim SELECT yog ib qho tseem ceeb ntawm 3-phase cardiovascular cov txiaj ntsig sim uas kawm txog kev ua tau zoo ntawm semaglutide 2.4 mg ib zaug hauv ib lub lis piam rau cov neeg laus rog rog lossis rog uas muaj kab mob plawv (CVD) tab sis tsis muaj keeb kwm ntawm ntshav qab zib. Cov txiaj ntsig tau sim tau pom tias semaglutide 2.4 mg tau ua tiav 20% txo qhov kev pheej hmoo ntawm cov teeb meem mob plawv loj (MACE) nyob rau lub sijhawm mus txog 5 xyoos, uas yog qhov tseem ceeb hauv kev txheeb cais.

Tsis tas li ntawd, semaglutide tau raug pov thawj los txo qhov kev pheej hmoo ntawm kev mob plawv tsis zoo hauv cov neeg mob ntshav qab zib. Thaum Lub Peb Hlis 9, 2024, US FDA tau tshaj tawm qhov kev pom zoo ntawm qhov qhia tshiab rau semaglutide - txhawm rau txo qhov kev pheej hmoo ntawm cov hlab plawv tuag, plawv nres, thiab mob stroke rau cov neeg laus uas muaj kab mob plawv thiab rog lossis rog.

Hauv cov ntsiab lus, raws li GLP-1RA, semaglutide tsis yog tsuas yog ua tau zoo hauv kev txo cov ntshav qab zib xwb tab sis kuj qhia tau hais tias muaj txiaj ntsig zoo hauv kev tiv thaiv kab mob plawv thiab txo qis kev pheej hmoo ntawm cov hlab plawv, muab kev kho mob tshiab rau cov neeg mob ntshav qab zib hom 2.

GenoHope Biotech Co., Ltd.
Ib lub tuam txhab ua lag luam ntawm GLP-1 API
Pom zoo los ntawm FDA
Zoo siab txais tos txhua qhov kev nug
WhatsApp / Tel: +8613833133635
Email:info@genohopebio.com